Tirzepatide is a synthetic 39-amino-acid linear peptide that acts as a dual agonist at both the glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. A C20 fatty diacid moiety conjugated via a linker at Lys20 confers albumin binding and an extended half-life. The dual incretin mechanism is studied for its combined effect on insulin secretion, glucose disposal, gastric emptying, and appetite regulation in experimental metabolic models.
| Scientific name | Tirzepatide Acetate |
|---|---|
| CAS number | 2023788-19-2 |
| Molecular formula | C225H348N48O68 |
| Molecular weight | 4813.45 g/mol |
| Sequence | Tyr-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-Ala-Leu-Asp-Lys-Ile-Ala-Gln-Lys-Ala-Phe-Val-Gln-Trp-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 |
| Form | Lyophilized Powder |
| HPLC purity | 99.5% |
Store lyophilized powder at -20°C for up to 2 years. Protect from ambient humidity and direct sunlight. Once reconstituted, store at 2°C to 8°C (refrigerated) and use within 14 days.
Add 2.0 mL of Sterile Bacteriostatic Water slowly down the inside wall of the vial. Do not spray directly onto the powder. Swirl gently in a circular motion until a clear, colorless solution forms. Do not shake.
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For laboratory research use only. Products are not approved by the FDA or EMA for human or veterinary use, and are not drugs, dietary supplements or cosmetics.