PT-141 (Bremelanotide) is a cyclic heptapeptide analogue of alpha-MSH and an active metabolite of Melanotan II. Unlike its parent compound, it lacks the C-terminal amide and shows markedly reduced pigmentary activity. It acts as a non-selective agonist at melanocortin receptors, with principal research interest in MC3R and MC4R signalling within the central nervous system rather than peripheral melanogenesis.
| Scientific name | Bremelanotide Acetate |
|---|---|
| CAS number | 189691-06-3 |
| Molecular formula | C50H68N14O10 |
| Molecular weight | 1025.2 g/mol |
| Sequence | Ac-Nle-cyclo(Asp-His-D-Phe-Arg-Trp-Lys)-OH |
| Form | Lyophilized Powder |
| HPLC purity | 99.5% |
Store lyophilized powder at -20°C for up to 24 months, protected from light. Once reconstituted, store at 2°C to 8°C and use within 14 days.
Add 2.0 mL of Sterile Bacteriostatic Water slowly down the vial wall. Swirl gently until fully dissolved into a clear, colorless solution. Do not shake vigorously.
Certificate of Analysis (COA) for PT-141 (Bremelanotide)
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For laboratory research use only. Products are not approved by the FDA or EMA for human or veterinary use, and are not drugs, dietary supplements or cosmetics.