Sermorelin is the amidated 1-29 fragment of human growth hormone-releasing hormone — the shortest sequence that retains full biological activity at the GHRH receptor. Because it acts upstream on the pituitary rather than supplying growth hormone directly, endogenous feedback loops via somatostatin remain intact, which makes it a preferred tool for studying physiological GH pulsatility and pituitary reserve.
| Scientific name | GHRH(1-29) Amide |
|---|---|
| CAS number | 86168-78-7 |
| Molecular formula | C149H246N44O42S |
| Molecular weight | 3357.9 g/mol |
| Sequence | Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2 |
| Form | Lyophilized Powder |
| HPLC purity | 99.5% |
Store lyophilized powder at -20°C for up to 24 months. Once reconstituted, keep refrigerated at 2°C to 8°C and use within 14 days. Protect from light at all times.
Slowly add 2.0 mL of Sterile Bacteriostatic Water along the glass wall of the vial. Allow to rest for 2 minutes, then swirl gently until the solution is completely clear. Do not shake.
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For laboratory research use only. Products are not approved by the FDA or EMA for human or veterinary use, and are not drugs, dietary supplements or cosmetics.