PT-141 (Bremelanotide) 10mg — Melanocortin Receptor Agonist Research Peptide

PT-141 (Bremelanotide) is a cyclic heptapeptide analogue of alpha-MSH and an active metabolite of Melanotan II. Unlike its parent compound, it lacks the C-terminal amide and shows markedly reduced pigmentary activity. It acts as a non-selective agonist at melanocortin receptors, with principal research interest in MC3R and MC4R signalling within the central nervous system rather than peripheral melanogenesis.

Specifications

Scientific name	Bremelanotide Acetate
CAS number	189691-06-3
Molecular formula	C50H68N14O10
Molecular weight	1025.2 g/mol
Sequence	Ac-Nle-cyclo(Asp-His-D-Phe-Arg-Trp-Lys)-OH
Form	Lyophilized Powder
HPLC purity	99.5%

Research applications

• Non-selective melanocortin receptor agonist with MC3R/MC4R research focus.
• Cyclic backbone confers high metabolic stability compared to linear analogues.
• Studied for centrally mediated signalling rather than peripheral pigmentation.
• Well-characterised reference compound in melanocortin pathway assays.

Storage

Store lyophilized powder at -20°C for up to 24 months, protected from light. Once reconstituted, store at 2°C to 8°C and use within 14 days.

Reconstitution

Add 2.0 mL of Sterile Bacteriostatic Water slowly down the vial wall. Swirl gently until fully dissolved into a clear, colorless solution. Do not shake vigorously.

Certificate of Analysis (COA) for PT-141 (Bremelanotide)

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For laboratory research use only. Products are not approved by the FDA or EMA for human or veterinary use, and are not drugs, dietary supplements or cosmetics.